SCOPe 2.06: Domain d3rbbc_: 3rbb C:

Lineage for d3rbbc_ (3rbb C:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.102: Regulatory factor Nef [55670] (1 superfamily)
   alpha(2)-beta(4)-alpha; 3 layers: alpha/beta/alpha

4. Superfamily d.102.1: Regulatory factor Nef [55671] (2 families)

5. Family d.102.1.1: Regulatory factor Nef [55672] (2 proteins)
   automatically mapped to Pfam PF00469

6. Protein automated matches [191288] (2 species)
   not a true protein

7. Species Hiv-1 m:b_arv2/sf2 [TaxId:11685] [189936] (4 PDB entries)

8. Domain d3rbbc_: 3rbb C: [184876]
   Other proteins in same PDB: d3rbbb_, d3rbbd_
   automated match to d2nefa_
   complexed with edo

Details for d3rbbc_

PDB Entry: 3rbb, 2.35 Å

PDB Description: HIV-1 NEF protein in complex with engineered HCK SH3 domain

PDB Compounds: (C:) Protein Nef

SCOPe Domain Sequences for d3rbbc_:

Sequence, based on SEQRES records:

>d3rbbc_ d.102.1.1 (C:) automated matches {Hiv-1 m:b_arv2/sf2 [TaxId: 11685]}
evgfpvrpqvplrpmtykaaldishflkekgglegliwsqrrqeildlwiyhtqgyfpdw
qnytpgpgirypltfgwcfklvpvepekveeanegennsllhpmslhgmedaekevlvwr
fdsklafhhmarelhpeyyk

Sequence, based on observed residues (ATOM records):

>d3rbbc_ d.102.1.1 (C:) automated matches {Hiv-1 m:b_arv2/sf2 [TaxId: 11685]}
evgfpvrpqvplrpmtykaaldishflkekgglegliwsqrrqeildlwiyhtqgyfpdw
qnytpgpgirypltfgwcfklvpvepeksllhpmaekevlvwrfdsklafhhmarelhpe
yyk

Timeline for d3rbbc_:

• d3rbbc_ first appeared in SCOPe 2.01
  
• d3rbbc_ appears in SCOPe 2.05
  
• d3rbbc_ appears in SCOPe 2.07
  
• d3rbbc_ appears in the current release, SCOPe 2.08