SCOPe 2.05: Domain d3r8ia_: 3r8i A:

Lineage for d3r8ia_ (3r8i A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (94 PDB entries)
   Uniprot P37231 232-505

8. Domain d3r8ia_: 3r8i A: [184847]
   automated match to d1nyxa_
   protein/DNA complex; complexed with xcx

Details for d3r8ia_

PDB Entry: 3r8i, 2.3 Å

PDB Description: Crystal Structure of PPARgamma with an achiral ureidofibrate derivative (RT86)

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3r8ia_:

Sequence; same for both SEQRES and ATOM records:

>d3r8ia_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdl

Timeline for d3r8ia_:

• d3r8ia_ first appeared in SCOPe 2.01
  
• d3r8ia_ appears in SCOPe 2.04
  
• d3r8ia_ appears in SCOPe 2.06
  
• d3r8ia_ appears in the current release, SCOPe 2.08