SCOPe 2.05: Domain d3r5ib_: 3r5i B:

Lineage for d3r5ib_ (3r5i B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.1: Globin-like [46457] (2 superfamilies)
   core: 6 helices; folded leaf, partly opened

4. Superfamily a.1.1: Globin-like [46458] (5 families)

5. Family a.1.1.2: Globins [46463] (27 proteins)
   Heme-binding protein

6. Protein Hemoglobin, beta-chain [46500] (24 species)

7. Species Human (Homo sapiens) [TaxId:9606] [46501] (225 PDB entries)
   Uniprot P68871

8. Domain d3r5ib_: 3r5i B: [184811]
   Other proteins in same PDB: d3r5ia_, d3r5ic_
   automated match to d1dxtb_
   complexed with 3r5, hem, oxy, so4

Details for d3r5ib_

PDB Entry: 3r5i, 2.2 Å

PDB Description: Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312

PDB Compounds: (B:) Hemoglobin subunit beta

SCOPe Domain Sequences for d3r5ib_:

Sequence; same for both SEQRES and ATOM records:

>d3r5ib_ a.1.1.2 (B:) Hemoglobin, beta-chain {Human (Homo sapiens) [TaxId: 9606]}
vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
eftppvqaayqkvvagvanalahkyh

Timeline for d3r5ib_:

• d3r5ib_ first appeared in SCOPe 2.01
  
• d3r5ib_ appears in SCOPe 2.04
  
• d3r5ib_ appears in SCOPe 2.06
  
• d3r5ib_ appears in the current release, SCOPe 2.08