SCOPe 2.02: Domain d3qs4a_: 3qs4 A:

Lineage for d3qs4a_ (3qs4 A:)

1. Root: SCOPe 2.02

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein automated matches [190994] (2 species)
   not a true protein

7. Species Aquifex aeolicus [TaxId:63363] [188708] (18 PDB entries)

8. Domain d3qs4a_: 3qs4 A: [184605]
   automated match to d2a65a1
   complexed with bog, na, trp; mutant

Details for d3qs4a_

PDB Entry: 3qs4, 2.63 Å

PDB Description: crystal structure of leut mutant f259v bound to sodium and l- tryptophan

PDB Compounds: (A:) Na(+):neurotransmitter symporter (Snf family)

SCOPe Domain Sequences for d3qs4a_:

Sequence, based on SEQRES records:

>d3qs4a_ f.54.1.1 (A:) automated matches {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsili
rgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvw
iaavgqifftlslgvgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaava
ffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmi
afledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiff
wifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvw
itrfyiiglflfltflvflaerrrnhe

Sequence, based on observed residues (ATOM records):

>d3qs4a_ f.54.1.1 (A:) automated matches {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgi
skgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaa
vgqifftlslgvgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaffg
vanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafl
edelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwif
gadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwitr
fyiiglflfltflvflaerrrnhe

Timeline for d3qs4a_:

• d3qs4a_ first appeared in SCOPe 2.01
  
• d3qs4a_ appears in SCOPe 2.03
  
• d3qs4a_ appears in the current release, SCOPe 2.08