SCOPe 2.08: Domain d3qqud_: 3qqu D:

Lineage for d3qqud_ (3qqu D:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (18 PDB entries)

8. Domain d3qqud_: 3qqu D: [184589]
   automated match to d1jqha_
   complexed with 01p

Details for d3qqud_

PDB Entry: 3qqu, 2.9 Å

PDB Description: Cocrystal structure of unphosphorylated igf with pyrimidine 8

PDB Compounds: (D:) insulin-like growth factor 1 receptor

SCOPe Domain Sequences for d3qqud_:

Sequence, based on SEQRES records:

>d3qqud_ d.144.1.7 (D:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
pdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreriefl
neasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvlapps
lskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrk
ggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmeg
glldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

Sequence, based on observed residues (ATOM records):

>d3qqud_ d.144.1.7 (D:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
pdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmreriefl
neasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemlappslskmi
qmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgl
lpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldk
pdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

Timeline for d3qqud_:

• d3qqud_ first appeared in SCOPe 2.01
  
• d3qqud_ appears in SCOPe 2.07