SCOPe 2.01: Domain d3qlwa_: 3qlw A:

Lineage for d3qlwa_ (3qlw A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductases, eukaryotic type [53605] (6 species)

7. Species Yeast (Candida albicans) [TaxId:5476] [53609] (12 PDB entries)

8. Domain d3qlwa_: 3qlw A: [184480]
   automated match to d1ai9a_
   complexed with n22, nap

Details for d3qlwa_

PDB Entry: 3qlw, 2.5 Å

PDB Description: Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (UCP120B)

PDB Compounds: (A:) Putative uncharacterized protein CaJ7.0360

SCOPe Domain Sequences for d3qlwa_:

Sequence; same for both SEQRES and ATOM records:

>d3qlwa_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Yeast (Candida albicans) [TaxId: 5476]}
kpnvaiivaalkpalgigykgkmpwrlrkeiryfkdvttrttkpntrnavimgrktwesi
pqkfrplpdrlniilsrsyeneiiddniihassiesslnlvsdvervfiiggaeiyneli
nnslvshlliteiehpspesiemdtflkfpleswtkqpkselqkfvgdtvleddikegdf
tynytlwtrk

Timeline for d3qlwa_:

• d3qlwa_ is new in SCOPe 2.01-stable
  
• d3qlwa_ appears in SCOPe 2.02
  
• d3qlwa_ appears in the current release, SCOPe 2.08