SCOPe 2.07: Domain d3qlsa1: 3qls A:3-192

Lineage for d3qlsa1 (3qls A:3-192)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)

7. Species Yeast (Candida albicans) [TaxId:5476] [53609] (17 PDB entries)

8. Domain d3qlsa1: 3qls A:3-192 [184478]
   Other proteins in same PDB: d3qlsa2, d3qlsb2
   automated match to d1ai9a_
   complexed with 55v, gly, gol, ndp

Details for d3qlsa1

PDB Entry: 3qls, 1.73 Å

PDB Description: candida albicans dihydrofolate reductase complexed with nadph and 6- methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1- yl]pyrimidine-2,4-diamine (ucp115a)

PDB Compounds: (A:) Putative uncharacterized protein CaJ7.0360

SCOPe Domain Sequences for d3qlsa1:

Sequence; same for both SEQRES and ATOM records:

>d3qlsa1 c.71.1.1 (A:3-192) Dihydrofolate reductases, eukaryotic type {Yeast (Candida albicans) [TaxId: 5476]}
kpnvaiivaalkpalgigykgkmpwrlrkeiryfkdvttrttkpntrnavimgrktwesi
pqkfrplpdrlniilsrsyeneiiddniihassiesslnlvsdvervfiiggaeiyneli
nnslvshlliteiehpspesiemdtflkfpleswtkqpkselqkfvgdtvleddikegdf
tynytlwtrk

Timeline for d3qlsa1:

• d3qlsa1 first appeared in SCOPe 2.01, called d3qlsa_
  
• d3qlsa1 appears in SCOPe 2.06
  
• d3qlsa1 appears in the current release, SCOPe 2.08