SCOPe 2.08: Domain d3qlrb1: 3qlr B:3-192

Lineage for d3qlrb1 (3qlr B:3-192)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)

7. Species Yeast (Candida albicans) [TaxId:5476] [53609] (17 PDB entries)

8. Domain d3qlrb1: 3qlr B:3-192 [184477]
   Other proteins in same PDB: d3qlra2, d3qlrb2
   automated match to d1ai9a_
   complexed with gly, gol, ndp, qlr

Details for d3qlrb1

PDB Entry: 3qlr, 2.15 Å

PDB Description: Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)

PDB Compounds: (B:) Putative uncharacterized protein CaJ7.0360

SCOPe Domain Sequences for d3qlrb1:

Sequence; same for both SEQRES and ATOM records:

>d3qlrb1 c.71.1.1 (B:3-192) Dihydrofolate reductases, eukaryotic type {Yeast (Candida albicans) [TaxId: 5476]}
kpnvaiivaalkpalgigykgkmpwrlrkeiryfkdvttrttkpntrnavimgrktwesi
pqkfrplpdrlniilsrsyeneiiddniihassiesslnlvsdvervfiiggaeiyneli
nnslvshlliteiehpspesiemdtflkfpleswtkqpkselqkfvgdtvleddikegdf
tynytlwtrk

Timeline for d3qlrb1:

• d3qlrb1 first appeared in SCOPe 2.01, called d3qlrb_
  
• d3qlrb1 appears in SCOPe 2.07