SCOPe 2.06: Domain d3qkka_: 3qkk A:

Lineage for d3qkka_ (3qkk A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d3qkka_: 3qkk A: [184470]
   automated match to d1o6ka_
   complexed with smh

Details for d3qkka_

PDB Entry: 3qkk, 2.3 Å

PDB Description: Spirochromane Akt Inhibitors

PDB Compounds: (A:) RAC-alpha serine/threonine-protein kinase

SCOPe Domain Sequences for d3qkka_:

Sequence, based on SEQRES records:

>d3qkka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlq
nsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldy
lhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevled
ndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgl
lkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeeft
aqmititppdqddsmecvdserrphfpqfdysass

Sequence, based on observed residues (ATOM records):

>d3qkka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlq
nsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldy
lhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevled
ndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgl
lkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeeft
aqmitimecvdserrphfpqfdysass

Timeline for d3qkka_:

• d3qkka_ first appeared in SCOPe 2.01
  
• d3qkka_ appears in SCOPe 2.05
  
• d3qkka_ appears in SCOPe 2.07
  
• d3qkka_ appears in the current release, SCOPe 2.08