SCOPe 2.08: Domain d1dgna_: 1dgn A:

Lineage for d1dgna_ (1dgn A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.77: DEATH domain [47985] (1 superfamily)
   6 helices: closed bundle; greek-key; internal pseudo twofold symmetry

4. Superfamily a.77.1: DEATH domain [47986] (5 families)

5. Family a.77.1.3: Caspase recruitment domain, CARD [81313] (7 proteins)

6. Protein Iceberg [48001] (1 species)
   an inhibitor of interleukin-1beta generation

7. Species Human (Homo sapiens) [TaxId:9606] [48002] (1 PDB entry)

8. Domain d1dgna_: 1dgn A: [18436]

Details for d1dgna_

PDB Entry: 1dgn

PDB Description: solution structure of iceberg, an inhibitor of interleukin-1beta generation

PDB Compounds: (A:) iceberg (protease inhibitor)

SCOPe Domain Sequences for d1dgna_:

Sequence; same for both SEQRES and ATOM records:

>d1dgna_ a.77.1.3 (A:) Iceberg {Human (Homo sapiens) [TaxId: 9606]}
adqllrkkrrifihsvgagtinalldclledevisqedmnkvrdendtvmdkarvlidlv
tgkgpkscckfikhlceedpqlaskmglh

Timeline for d1dgna_:

• d1dgna_ first appeared (with stable ids) in SCOP 1.55
  
• d1dgna_ appears in SCOPe 2.07