SCOPe 2.01: Domain d3q70a_: 3q70 A:

Lineage for d3q70a_ (3q70 A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Acid protease [50649] (9 species)

7. Species Yeast (Candida albicans) [TaxId:5476] [50653] (4 PDB entries)

8. Domain d3q70a_: 3q70 A: [184236]
   automated match to d1eaga_
   complexed with mrd, rit, zn

Details for d3q70a_

PDB Entry: 3q70, 1.4 Å

PDB Description: Secreted aspartic protease in complex with ritonavir

PDB Compounds: (A:) Candidapepsin-2

SCOPe Domain Sequences for d3q70a_:

Sequence, based on SEQRES records:

>d3q70a_ b.50.1.2 (A:) Acid protease {Yeast (Candida albicans) [TaxId: 5476]}
qavpvtlhneqvtyaaditvgsnnqklnvivdtgssdlwvpdvnvdcqvtysdqtadfck
qkgtydpsgssasqdlntpfkigygdgsssqgtlykdtvgfggvsiknqvladvdstsid
qgilgvgyktneaggsydnvpvtlkkqgviaknayslylnspdaatgqiifggvdnakys
gslialpvtsdrelrislgsvevsgktintdnvdvlldsgttitylqqdladqiikafng
kltqdsngnsfyevdcnlsgdvvfnfsknakisvpasefaaslqgddgqpydkcqllfdv
ndanilgdnflrsayivydlddneislaqvkytsassisalt

Sequence, based on observed residues (ATOM records):

>d3q70a_ b.50.1.2 (A:) Acid protease {Yeast (Candida albicans) [TaxId: 5476]}
qavpvtlhneqvtyaaditvgsnnqklnvivdtgssdlwvpdvnvdcqvtysdqtadfck
qkgtydpsgssasqdlntpfkigygdgsssqgtlykdtvgfggvsiknqvladvdstsid
qgilgvgyktneaggsydnvpvtlkkqgviaknayslylnspdaatgqiifggvdnakys
gslialpvtsdrelrislgsvevsgktintdnvdvlldsgttitylqqdladqiikafng
kltqdsngnsfyevdcnlsgdvvfnfsknakisvpasefaasldkcqllfdvndanilgd
nflrsayivydlddneislaqvkytsassisalt

Timeline for d3q70a_:

• d3q70a_ is new in SCOPe 2.01-stable
  
• d3q70a_ appears in SCOPe 2.02
  
• d3q70a_ appears in the current release, SCOPe 2.08