SCOPe 2.01: Domain d3q5ha_: 3q5h A:

Lineage for d3q5ha_ (3q5h A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (40 PDB entries)

8. Domain d3q5ha_: 3q5h A: [184221]
   automated match to d1bila_
   complexed with cl, rx6

Details for d3q5ha_

PDB Entry: 3q5h, 2.16 Å

PDB Description: clinically useful alkyl amine renin inhibitors

PDB Compounds: (A:) renin

SCOPe Domain Sequences for d3q5ha_:

Sequence; same for both SEQRES and ATOM records:

>d3q5ha_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhkl
fdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlae
fdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdp
qhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklm
ealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaiham
dippptgptwalgatfirkfytefdrrnnrigfalar

Timeline for d3q5ha_:

• d3q5ha_ is new in SCOPe 2.01-stable
  
• d3q5ha_ appears in SCOPe 2.02
  
• d3q5ha_ appears in the current release, SCOPe 2.08