SCOPe 2.06: Domain d3q4za1: 3q4z A:251-545

Lineage for d3q4za1 (3q4z A:251-545)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein pak1 [56146] (1 species)
   OPK group; PAK/STE20 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56147] (19 PDB entries)

8. Domain d3q4za1: 3q4z A:251-545 [184214]
   Other proteins in same PDB: d3q4za2
   automated match to d1f3mc_
   complexed with anp, mg

Details for d3q4za1

PDB Entry: 3q4z, 1.89 Å

PDB Description: Structure of unphosphorylated PAK1 kinase domain

PDB Compounds: (A:) Serine/threonine-protein kinase PAK 1

SCOPe Domain Sequences for d3q4za1:

Sequence, based on SEQRES records:

>d3q4za1 d.144.1.7 (A:251-545) pak1 {Human (Homo sapiens) [TaxId: 9606]}
eeileklriivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpkke
liineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavc
reclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpyw
mapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpekl
saifrdflnrclemdvekrgsakeliqhqflkiakplssltpliaaakeatknnh

Sequence, based on observed residues (ATOM records):

>d3q4za1 d.144.1.7 (A:251-545) pak1 {Human (Homo sapiens) [TaxId: 9606]}
eeileklriivsvgdpkfekigqgasgtvytamdqevairqmnlkeliineilvmrenkn
pnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcreclqaleflhsnq
vihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpywmapevvtrkaygpk
vdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnrclem
dvekrgsakeliqhqflkiakplssltpliaaakeatknnh

Timeline for d3q4za1:

• d3q4za1 first appeared in SCOPe 2.01, called d3q4za_
  
• d3q4za1 was called d3q4za_ in SCOPe 2.05
  
• d3q4za1 appears in SCOPe 2.07
  
• d3q4za1 appears in the current release, SCOPe 2.08