Lineage for d3q30a_ (3q30 A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2010547Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2010548Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2010672Family a.128.1.2: Squalene synthase [48580] (2 protein domains)
    automatically mapped to Pfam PF00494
  6. 2010678Protein automated matches [191305] (1 species)
    not a true protein
  7. 2010679Species Human (Homo sapiens) [TaxId:9606] [190011] (24 PDB entries)
  8. 2010709Domain d3q30a_: 3q30 A: [184177]
    automated match to d1ezfb_
    complexed with d61, mg, po4

Details for d3q30a_

PDB Entry: 3q30 (more details), 2 Å

PDB Description: human squalene synthase in complex with (2r,3r)-2-carboxymethoxy-3-[5- (2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl) pentyloxy]propionic acid
PDB Compounds: (A:) Squalene synthase

SCOPe Domain Sequences for d3q30a_:

Sequence, based on SEQRES records: (download)

>d3q30a_ a.128.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmtisvekkvp
llhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigma
efldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqktn
iirdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvit
ylsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmdatnmpavk
aiiyqymeeiyhripdsdpsssktrqiistirt

Sequence, based on observed residues (ATOM records): (download)

>d3q30a_ a.128.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lssslktcykylnqtsaaviqaldgemrnavcifylvlraldtleddmtisvekkvpllh
nfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigmaefl
dkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqktniir
dyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvityls
rlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmdatnmpavkaii
yqymeeiyhripdsdpsssktrqiistirt

SCOPe Domain Coordinates for d3q30a_:

Click to download the PDB-style file with coordinates for d3q30a_.
(The format of our PDB-style files is described here.)

Timeline for d3q30a_: