SCOPe 2.01: Domain d3pxka_: 3pxk A:

Lineage for d3pxka_ (3pxk A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d3pxka_: 3pxk A: [184059]
   automated match to d1mp8a_
   complexed with pxk, so4

Details for d3pxka_

PDB Entry: 3pxk, 1.79 Å

PDB Description: focal adhesion kinase catalytic domain in complex with pyrrolo[2,3- d]thiazole

PDB Compounds: (A:) PTK2 protein

SCOPe Domain Sequences for d3pxka_:

Sequence, based on SEQRES records:

>d3pxka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikwmapesi
nfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlysl
mtkcwaydpsrrprftelkaqlstileeekaqq

Sequence, based on observed residues (ATOM records):

>d3pxka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglpikwmapesinfrrftsasdvwmfgvc
mweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprfte
lkaqlstileeekaqq

Timeline for d3pxka_:

• d3pxka_ is new in SCOPe 2.01-stable
  
• d3pxka_ appears in SCOPe 2.02
  
• d3pxka_ appears in the current release, SCOPe 2.08