Lineage for d3pp1a_ (3pp1 A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1931583Protein automated matches [190091] (12 species)
    not a true protein
  7. 1931656Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)
  8. 1932096Domain d3pp1a_: 3pp1 A: [183918]
    automated match to d1s9ja_
    complexed with act, atp, izg, mg

Details for d3pp1a_

PDB Entry: 3pp1 (more details), 2.7 Å

PDB Description: crystal structure of the human mitogen-activated protein kinase kinase 1 (mek 1) in complex with ligand and mgatp
PDB Compounds: (A:) Dual specificity mitogen-activated protein kinase kinase 1

SCOPe Domain Sequences for d3pp1a_:

Sequence, based on SEQRES records: (download)

>d3pp1a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
melkdddfekiselgagnggvvfkvshkpsglvmarklihleikpairnqiirelqvlhe
cnspyivgfygafysdgeisicmehmdggsldqvlkkagripeqilgkvsiavikgltyl
rekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymsperlqgthy
svqsdiwsmglslvemavgrypipppdakelelmfgcqvegdaaetpprprtpgrplssy
gmdsrppmaifelldyivnepppklpsgvfslefqdfvnkcliknpaeradlkqlmvhaf
ikrsdaeevdfagwlcstigln

Sequence, based on observed residues (ATOM records): (download)

>d3pp1a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
melkdddfekiselgagnggvvfkvshkpsglvmarklihleikpairnqiirelqvlhe
cnspyivgfygafysdgeisicmehmdggsldqvlkkagripeqilgkvsiavikgltyl
rekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymsperlqgthy
svqsdiwsmglslvemavgrypipppdakelelmfpmaifelldyivnepppklpsgvfs
lefqdfvnkcliknpaeradlkqlmvhafikrsdaeevdfagwlcstigln

SCOPe Domain Coordinates for d3pp1a_:

Click to download the PDB-style file with coordinates for d3pp1a_.
(The format of our PDB-style files is described here.)

Timeline for d3pp1a_: