SCOPe 2.08: Domain d3pp0b_: 3pp0 B:

Lineage for d3pp0b_ (3pp0 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3pp0b_: 3pp0 B: [183917]
   automated match to d1m14a_
   complexed with 03q

Details for d3pp0b_

PDB Entry: 3pp0, 2.25 Å

PDB Description: crystal structure of the kinase domain of human her2 (erbb2).

PDB Compounds: (B:) Receptor tyrosine-protein kinase erbB-2

SCOPe Domain Sequences for d3pp0b_:

Sequence, based on SEQRES records:

>d3pp0b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
apnqallrilketelrkvkvlgsgafgtvykgiwipdgenvkipvaikvlrentspkank
eildeayvmagvgspyvsrllgicltstvqlvtqlmpygclldhvrenrgrlgsqdllnw
cmqiakgmsyledvrlvhrdlaarnvlvkspnhvkitdfglarlldideteyhadggkvp
ikwmalesilrrrfthqsdvwsygvtvwelmtfgakpydgipareipdllekgerlpqpp
ictidvymimvkcwmidsecrprfrelvsefsrmardpqrfvviqnedlgpaspldstfy
rsll

Sequence, based on observed residues (ATOM records):

>d3pp0b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
apnqallrilketelrkvkvlgsgafgtvykgiwipdgenvkipvaikvlrentspkank
eildeayvmagvgspyvsrllgicltstvqlvtqlmpygclldhvrenrgrlgsqdllnw
cmqiakgmsyledvrlvhrdlaarnvlvkspnhvkitdfglarlldideteyhagkvpik
wmalesilrrrfthqsdvwsygvtvwelmtfgakpydgipareipdllekgerlpqppic
tidvymimvkcwmidsecrprfrelvsefsrmardpqrfvviqnepldstfyrsll

Timeline for d3pp0b_:

• d3pp0b_ first appeared in SCOPe 2.01
  
• d3pp0b_ appears in SCOPe 2.07