SCOPe 2.05: Domain d3poka_: 3pok A:

Lineage for d3poka_ (3pok A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 proteins)

6. Protein Interleukin-1beta [50363] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50364] (25 PDB entries)
   Uniprot P01584 117-269

8. Domain d3poka_: 3pok A: [183911]
   automated match to d1ioba_
   mutant

Details for d3poka_

PDB Entry: 3pok, 1.7 Å

PDB Description: interleukin-1-beta lbt l3 mutant

PDB Compounds: (A:) interleukin-1 beta

SCOPe Domain Sequences for d3poka_:

Sequence, based on SEQRES records:

>d3poka_ b.42.1.2 (A:) Interleukin-1beta {Human (Homo sapiens) [TaxId: 9606]}
apvrslnctlrdsqqkslvmsgpyelkalhlqgqdmeqqvvfsmsfvqgeesndkipval
glkeknlylscvlgyidtnndgwiegdelyptlqlesvdpknypkkkmekrfvfnkiein
nklefesaqfpnwyistsqaenmpvflggtkggqditdftmqfvss

Sequence, based on observed residues (ATOM records):

>d3poka_ b.42.1.2 (A:) Interleukin-1beta {Human (Homo sapiens) [TaxId: 9606]}
apvrslnctlrdsqqkslvmsgpyelkalhlqgqdmeqqvvfsmsfvqgeesndkipval
glkeknlylscvlgyidtndelyptlqlesvdpknypkkkmekrfvfnkieinnklefes
aqfpnwyistsqaenmpvflggtkggqditdftmqfvss

Timeline for d3poka_:

• d3poka_ first appeared in SCOPe 2.01
  
• d3poka_ appears in SCOPe 2.04
  
• d3poka_ appears in SCOPe 2.06
  
• d3poka_ appears in the current release, SCOPe 2.08