SCOPe 2.06: Domain d3pneb_: 3pne B:

Lineage for d3pneb_ (3pne B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [82821] (235 PDB entries)
   Uniprot P29476 298-716

8. Domain d3pneb_: 3pne B: [183863]
   automated match to d1om4b_
   complexed with 8ax, act, h4b, hem, zn

Details for d3pneb_

PDB Entry: 3pne, 1.97 Å

PDB Description: structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(3-chlorophenyl)ethyl)amino) ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

PDB Compounds: (B:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d3pneb_:

Sequence, based on SEQRES records:

>d3pneb_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrkpedvrtkdqlfpla
kefldqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgr
iqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsq
liryagykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqipp
elvlevpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdy
cdnsrynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesf
ikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwkg

Sequence, based on observed residues (ATOM records):

>d3pneb_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpdvrtkdqlfplakefldqyy
ssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgriqwsklqv
fdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryagyk
qpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqippelvlevpi
rhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdnsryni
leevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmeney
rcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwkg

Timeline for d3pneb_:

• d3pneb_ first appeared in SCOPe 2.01
  
• d3pneb_ appears in SCOPe 2.05
  
• d3pneb_ appears in SCOPe 2.07
  
• d3pneb_ appears in the current release, SCOPe 2.08