Lineage for d3piza_ (3piz A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674366Domain d3piza_: 3piz A: [183780]
    automated match to d1k2pa_
    complexed with 03c

Details for d3piza_

PDB Entry: 3piz (more details), 2.21 Å

PDB Description: Crystal structure of BTK kinase domain complexed with (5-Amino-1-o-tolyl-1H-pyrazol-4-yl)-[3-(1-methanesulfonyl-piperidin-4-yl)-phenyl]-methanone
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d3piza_:

Sequence, based on SEQRES records: (download)

>d3piza_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmm
nlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceame
yleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlm
yskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytim
yscwhekaderptfkillsnildvmdees

Sequence, based on observed residues (ATOM records): (download)

>d3piza_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gygsweidpkdltflkelgtgvvkygkwrgqydvaikmisedefieeakvmmnlsheklv
qlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyleskqfl
hrdlaarnclvndqgvvkvsdfglfpvrwsppevlmyskfssksdiwafgvlmweiyslg
kmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptfkillsnildv
mdees

SCOPe Domain Coordinates for d3piza_:

Click to download the PDB-style file with coordinates for d3piza_.
(The format of our PDB-style files is described here.)

Timeline for d3piza_: