SCOPe 2.04: Domain d3owha_: 3owh A:

Lineage for d3owha_ (3owh A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.5: Flavoproteins [52218] (9 families)

5. Family c.23.5.3: Quinone reductase [52235] (4 proteins)
   binds FAD

6. Protein Quinone reductase type 2 (menadione reductase) [52240] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52241] (44 PDB entries)

8. Domain d3owha_: 3owh A: [183335]
   automated match to d1qr2a_
   complexed with 52x, fad, zn

Details for d3owha_

PDB Entry: 3owh, 2.28 Å

PDB Description: x-ray structural study of quinone reductase ii inhibition by compounds with micromolar to nanomolar range ic50 values

PDB Compounds: (A:) Ribosyldihydronicotinamide dehydrogenase [quinone]

SCOPe Domain Sequences for d3owha_:

Sequence; same for both SEQRES and ATOM records:

>d3owha_ c.23.5.3 (A:) Quinone reductase type 2 (menadione reductase) {Human (Homo sapiens) [TaxId: 9606]}
gkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtlsn
pevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvlc
qgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcgf
kvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhf

Timeline for d3owha_:

• d3owha_ first appeared in SCOPe 2.01
  
• d3owha_ appears in SCOPe 2.03
  
• d3owha_ appears in SCOPe 2.05
  
• d3owha_ appears in the current release, SCOPe 2.08