Lineage for d3ow3a_ (3ow3 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542663Protein cAMP-dependent PK, catalytic subunit [56116] (7 species)
    AGC group; PKA subfamily; serine/threonine kinase
  7. 2542709Species Mouse (Mus musculus) [TaxId:10090] [56119] (30 PDB entries)
  8. 2542712Domain d3ow3a_: 3ow3 A: [183328]
    automated match to d1cmke_
    complexed with smy

Details for d3ow3a_

PDB Entry: 3ow3 (more details), 1.9 Å

PDB Description: Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors
PDB Compounds: (A:) cAMP-dependent protein kinase catalytic subunit alpha

SCOPe Domain Sequences for d3ow3a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3ow3a_ d.144.1.7 (A:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
vkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamkil
dkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlrr
igrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkgr
twtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgk
vrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapf
ipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

SCOPe Domain Coordinates for d3ow3a_:

Click to download the PDB-style file with coordinates for d3ow3a_.
(The format of our PDB-style files is described here.)

Timeline for d3ow3a_: