SCOPe 2.05: Domain d3oswb_: 3osw B:

Lineage for d3oswb_ (3osw B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (94 PDB entries)
   Uniprot P37231 232-505

8. Domain d3oswb_: 3osw B: [183273]
   automated match to d1nyxa_
   complexed with pgo, xdi

Details for d3oswb_

PDB Entry: 3osw, 2.55 Å

PDB Description: crystal structure of ppargamma ligand binding domain in complex with tetrabromo-bisphenol a (tbbpa)

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3oswb_:

Sequence, based on SEQRES records:

>d3oswb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiyk

Sequence, based on observed residues (ATOM records):

>d3oswb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgedkkevairi
fqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvli
segqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgll
nvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikkteh
pllqeiyk

Timeline for d3oswb_:

• d3oswb_ first appeared in SCOPe 2.01
  
• d3oswb_ appears in SCOPe 2.04
  
• d3oswb_ appears in SCOPe 2.06
  
• d3oswb_ appears in the current release, SCOPe 2.08