SCOPe 2.08: Domain d3omob_: 3omo B:

Lineage for d3omob_ (3omo B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor beta [48521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48522] (27 PDB entries)

8. Domain d3omob_: 3omo B: [183180]
   automated match to d1l2ja_
   complexed with wv7

Details for d3omob_

PDB Entry: 3omo, 2.21 Å

PDB Description: Fragment-Based Design of novel Estrogen Receptor Ligands

PDB Compounds: (B:) Estrogen receptor beta

SCOPe Domain Sequences for d3omob_:

Sequence, based on SEQRES records:

>d3omob_ a.123.1.1 (B:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
speqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvels
lfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllat
tsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwviak
sgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydllleml

Sequence, based on observed residues (ATOM records):

>d3omob_ a.123.1.1 (B:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
speqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvels
lfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllat
tsrfrelklqhkeylcvkamillnssmyplvtaklahllnavtdalvwviaksgissqqq
smrlanllmllshvrhasnkgmehllnmkcknvvpvydllleml

Timeline for d3omob_:

• d3omob_ first appeared in SCOPe 2.01
  
• d3omob_ appears in SCOPe 2.07