SCOPe 2.01: Domain d3oewa_: 3oew A:

Lineage for d3oewa_ (3oew A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (10 species)

7. Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (36 PDB entries)

8. Domain d3oewa_: 3oew A: [182969]
   automated match to d1bvra_
   complexed with mpd, nad

Details for d3oewa_

PDB Entry: 3oew, 2.2 Å

PDB Description: Crystal structure of wild-type InhA:NADH complex

PDB Compounds: (A:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d3oewa_:

Sequence; same for both SEQRES and ATOM records:

>d3oewa_ c.2.1.2 (A:) Enoyl-ACP reductase {Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]}
glldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplle
ldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihi
saysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagky
gvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvaktv
callsdwlpattgdiiyadggahtqll

Timeline for d3oewa_:

• d3oewa_ is new in SCOPe 2.01-stable
  
• d3oewa_ appears in SCOPe 2.02
  
• d3oewa_ appears in the current release, SCOPe 2.08