Lineage for d3octa_ (3oct A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 1931583Protein automated matches [190091] (12 species)
    not a true protein
  7. 1931656Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)
  8. 1931778Domain d3octa_: 3oct A: [182941]
    automated match to d1k2pa_
    complexed with 1n1; mutant

Details for d3octa_

PDB Entry: 3oct (more details), 1.95 Å

PDB Description: Crystal structure of bruton's tyrosine kinase mutant V555R in complex with dasatinib
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d3octa_:

Sequence, based on SEQRES records: (download)

>d3octa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnls
heklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyle
skqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssrgskfpvrwsppevlmysk
fssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimysc
whekaderptfkillsnildvmd

Sequence, based on observed residues (ATOM records): (download)

>d3octa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sweidpkdltflkelgqfgvvkygkwrgqydvaikmikmsedefieeakvmmnlsheklv
qlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyleskqfl
hrdlaarnclvndqgvvkvsdfglsrfpvrwsppevlmyskfssksdiwafgvlmweiys
lgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptfkillsnil
dvmd

SCOPe Domain Coordinates for d3octa_:

Click to download the PDB-style file with coordinates for d3octa_.
(The format of our PDB-style files is described here.)

Timeline for d3octa_: