Lineage for d3ocsa1 (3ocs A:395-656)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221112Domain d3ocsa1: 3ocs A:395-656 [182940]
    Other proteins in same PDB: d3ocsa2
    automated match to d1k2pa_
    complexed with 746, bme, so4

Details for d3ocsa1

PDB Entry: 3ocs (more details), 1.8 Å

PDB Description: Crystal structure of bruton's tyrosine kinase in complex with inhibitor CGI1746
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d3ocsa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3ocsa1 d.144.1.7 (A:395-656) automated matches {Human (Homo sapiens) [TaxId: 9606]}
weidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnlsh
eklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyles
kqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmyskf
ssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscw
hekaderptfkillsnildvmd

SCOPe Domain Coordinates for d3ocsa1:

Click to download the PDB-style file with coordinates for d3ocsa1.
(The format of our PDB-style files is described here.)

Timeline for d3ocsa1:

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Domains from same chain:
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d3ocsa2