SCOPe 2.01: Domain d3ocba_: 3ocb A:

Lineage for d3ocba_ (3ocb A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d3ocba_: 3ocb A: [182927]
   automated match to d1o6ka_
   complexed with xm1

Details for d3ocba_

PDB Entry: 3ocb, 2.7 Å

PDB Description: Akt1 kinase domain with pyrrolopyrimidine inhibitor

PDB Compounds: (A:) v-akt murine thymoma viral oncogene homolog 1 (AKT1)

SCOPe Domain Sequences for d3ocba_:

Sequence, based on SEQRES records:

>d3ocba_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlq
nsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldy
lhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevled
ndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgl
lkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeeft
aqmititppdqddsmecvdserrphfpqfdysass

Sequence, based on observed residues (ATOM records):

>d3ocba_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlq
nsrhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldy
lhseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevled
ndygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgl
lkkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeeft
aqmrphfpqfdysass

Timeline for d3ocba_:

• d3ocba_ is new in SCOPe 2.01-stable
  
• d3ocba_ appears in SCOPe 2.02
  
• d3ocba_ appears in the current release, SCOPe 2.08