SCOPe 2.07: Domain d3o6ob_: 3o6o B:

Lineage for d3o6ob_ (3o6o B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein automated matches [190229] (13 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [189431] (2 PDB entries)

8. Domain d3o6ob_: 3o6o B: [182840]
   Other proteins in same PDB: d3o6oa2
   automated match to d1uy6a_
   complexed with 1pe, 94m

Details for d3o6ob_

PDB Entry: 3o6o, 2 Å

PDB Description: crystal structure of the n-terminal domain of an hsp90 from trypanosoma brucei, tb10.26.1080 in the presence of an the inhibitor biib021

PDB Compounds: (B:) Heat shock protein 83

SCOPe Domain Sequences for d3o6ob_:

Sequence, based on SEQRES records:

>d3o6ob_ d.122.1.1 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mtetfafqaeinqlmsliintfysnkeiflrelisnssdacdkiryqsltnqsvlgdeph
lrirvipdrvnktltvedsgigmtkadlvnnlgtiarsgtksfmealeaggdmsmigqfg
vgfysaylvadrvtvvsknneddaytwessaggtftvtstpdcdlkrgtrivlhlkedqq
eyleerrlkdlikkhsefigydielmv

Sequence, based on observed residues (ATOM records):

>d3o6ob_ d.122.1.1 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mtetfafqaeinqlmsliintfysnkeiflrelisnssdacdkiryqsltnqsvlgdeph
lrirvipdrvnktltvedsgigmtkadlvnnlgtiarsgtksfmealeaggdmsmigqfg
vgfysaylvadrvtvvsknneddaytwessaggtftvtstpdlkrgtrivlhlkedqqey
leerrlkdlikkhsefigydielmv

Timeline for d3o6ob_:

• d3o6ob_ first appeared in SCOPe 2.01
  
• d3o6ob_ appears in SCOPe 2.06
  
• d3o6ob_ appears in the current release, SCOPe 2.08