SCOPe 2.07: Domain d3nz0a1: 3nz0 A:888-1176

Lineage for d3nz0a1 (3nz0 A:888-1176)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d3nz0a1: 3nz0 A:888-1176 [182635]
   Other proteins in same PDB: d3nz0a2
   automated match to d1u46a_
   complexed with iza

Details for d3nz0a1

PDB Entry: 3nz0, 2 Å

PDB Description: Non-phosphorylated TYK2 kinase with CMP6

PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d3nz0a1:

Sequence, based on SEQRES records:

>d3nz0a1 d.144.1.0 (A:888-1176) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhrsgwkqe
idilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtvlrltel
lergerlprpdkcpcevyhlmkncweteasfrptfenlipilktvheky

Sequence, based on observed residues (ATOM records):

>d3nz0a1 d.144.1.0 (A:888-1176) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadcgpqhrsgwkqe
idilrtlyhehiikykgccedqgekslqlvmeyvplgslrdylprhsiglaqlllfaqqi
cegmaylhaqhyihrnlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfw
yapeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligtvlrltellerger
lprpdkcpcevyhlmkncweteasfrptfenlipilktvheky

Timeline for d3nz0a1:

• d3nz0a1 first appeared in SCOPe 2.01, called d3nz0a_
  
• d3nz0a1 appears in SCOPe 2.06
  
• d3nz0a1 appears in the current release, SCOPe 2.08