SCOPe 2.08: Domain d3nw2b_: 3nw2 B:

Lineage for d3nw2b_ (3nw2 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [56515] (43 PDB entries)
   Uniprot P29477 77-496 ! Uniprot P29477 77-495

8. Domain d3nw2b_: 3nw2 B: [182584]
   automated match to d1jwja_
   complexed with h4b, hem, mpw, so4

Details for d3nw2b_

PDB Entry: 3nw2, 2.8 Å

PDB Description: novel nanomolar imidazopyridines as selective nitric oxide synthase (inos) inhibitors: sar and structural insights

PDB Compounds: (B:) Nitric oxide synthase, inducible

SCOPe Domain Sequences for d3nw2b_:

Sequence, based on SEQRES records:

>d3nw2b_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
qyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprdkptpleellph
aiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcig
riqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwns
qliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeip
pdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrd
fcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtases
fmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwq

Sequence, based on observed residues (ATOM records):

>d3nw2b_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
qyvriknwgsgeilhdtlhhkatssclgsimnpksltrgprdkptpleellphaiefinq
yygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqwsnl
qvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqliryag
yqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlvlev
tmehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdtqry
nileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkhmqn
eyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwq

Timeline for d3nw2b_:

• d3nw2b_ first appeared in SCOPe 2.01
  
• d3nw2b_ appears in SCOPe 2.07