SCOPe 2.01: Domain d3nw2a_: 3nw2 A:

Lineage for d3nw2a_ (3nw2 A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [56515] (43 PDB entries)
   Uniprot P29477 77-496 ! Uniprot P29477 77-495

8. Domain d3nw2a_: 3nw2 A: [182583]
   automated match to d1jwja_
   complexed with h4b, hem, mpw, so4

Details for d3nw2a_

PDB Entry: 3nw2, 2.8 Å

PDB Description: novel nanomolar imidazopyridines as selective nitric oxide synthase (inos) inhibitors: sar and structural insights

PDB Compounds: (A:) Nitric oxide synthase, inducible

SCOPe Domain Sequences for d3nw2a_:

Sequence, based on SEQRES records:

>d3nw2a_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
qyvriknwgsgeilhdtlhhkatsdftcksksclgsimnpksltrgprdkptpleellph
aiefinqyygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcig
riqwsnlqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwns
qliryagyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeip
pdlvlevtmehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrd
fcdtqrynileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtases
fmkhmqneyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwq

Sequence, based on observed residues (ATOM records):

>d3nw2a_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Mouse (Mus musculus) [TaxId: 10090]}
qyvriknwgsgeilhdtlhhkatsdsclgsimnpksltrgprdkptpleellphaiefin
qyygsfkeakieehlarleavtkeiettgtyqltldelifatkmawrnaprcigriqwsn
lqvfdarncstaqemfqhicrhilyatnngnirsaitvfpqrsdgkhdfrlwnsqlirya
gyqmpdgtirgdaatleftqlcidlgwkprygrfdvlplvlqadgqdpevfeippdlvle
vtmehpkyewfqelglkwyalpavanmllevgglefpacpfngwymgteigvrdfcdtqr
ynileevgrrmglethtlaslwkdravteinvavlhsfqkqnvtimdhhtasesfmkhmq
neyrarggcpadwiwlvppvsgsitpvfhqemlnyvlspfyyyqiepwkthiwq

Timeline for d3nw2a_:

• d3nw2a_ is new in SCOPe 2.01-stable
  
• d3nw2a_ appears in SCOPe 2.02
  
• d3nw2a_ appears in the current release, SCOPe 2.08