SCOPe 2.05: Domain d3ncla_: 3ncl A:

Lineage for d3ncla_ (3ncl A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Matriptase MTSP1 [69284] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69285] (18 PDB entries)

8. Domain d3ncla_: 3ncl A: [182144]
   automated match to d1eawa_
   complexed with ccz, fmt

Details for d3ncla_

PDB Entry: 3ncl, 1.19 Å

PDB Description: crystal structure of mt-sp1 bound to benzamidine phosphonate inhibitor

PDB Compounds: (A:) Suppressor of tumorigenicity 14 protein

SCOPe Domain Sequences for d3ncla_:

Sequence; same for both SEQRES and ATOM records:

>d3ncla_ b.47.1.2 (A:) Matriptase MTSP1 {Human (Homo sapiens) [TaxId: 9606]}
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpislpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
v

Timeline for d3ncla_:

• d3ncla_ first appeared in SCOPe 2.01
  
• d3ncla_ appears in SCOPe 2.04
  
• d3ncla_ appears in SCOPe 2.06
  
• d3ncla_ appears in the current release, SCOPe 2.08