Lineage for d3n81g_ (3n81 G:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1875571Fold c.82: ALDH-like [53719] (1 superfamily)
    consists of two similar domains with 3 layers (a/b/a) each; duplication
    core: parallel beta-sheet of 5 strands, order 32145
  4. 1875572Superfamily c.82.1: ALDH-like [53720] (3 families) (S)
    binds NAD differently from other NAD(P)-dependent oxidoreductases
  5. 1875573Family c.82.1.1: ALDH-like [53721] (6 proteins)
  6. 1875578Protein Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)
  7. 1875602Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (25 PDB entries)
    Uniprot P05091
  8. 1875649Domain d3n81g_: 3n81 G: [181993]
    automated match to d1bi9a_
    complexed with edo, gai, na; mutant

Details for d3n81g_

PDB Entry: 3n81 (more details), 1.7 Å

PDB Description: t244a mutant of human mitochondrial aldehyde dehydrogenase, apo form
PDB Compounds: (G:) aldehyde dehydrogenase, mitochondrial

SCOPe Domain Sequences for d3n81g_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3n81g_ c.82.1.1 (G:) Aldehyde reductase (dehydrogenase), ALDH {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
vpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvdkavkaar
aafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylvdldmvlk
clryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklgpalatgn
vvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdkvafagst
eigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgqcccagsr
tfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintgkqegakl
lcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgrannstygl
aaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgeyglqayte
vktvtvkvpqkns

SCOPe Domain Coordinates for d3n81g_:

Click to download the PDB-style file with coordinates for d3n81g_.
(The format of our PDB-style files is described here.)

Timeline for d3n81g_: