Lineage for d3n3gb_ (3n3g B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154672Protein (Pro)cathepsin S [82566] (1 species)
  7. 2154673Species Human (Homo sapiens) [TaxId:9606] [82567] (23 PDB entries)
  8. 2154683Domain d3n3gb_: 3n3g B: [181872]
    automated match to d1ms6a_
    complexed with 935, 93n, dms, gol, peg, so4

Details for d3n3gb_

PDB Entry: 3n3g (more details), 1.6 Å

PDB Description: 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important
PDB Compounds: (B:) cathepsin S

SCOPe Domain Sequences for d3n3gb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3n3gb_ d.3.1.1 (B:) (Pro)cathepsin S {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3n3gb_:

Click to download the PDB-style file with coordinates for d3n3gb_.
(The format of our PDB-style files is described here.)

Timeline for d3n3gb_: