SCOPe 2.05: Domain d3mz6a_: 3mz6 A:

Lineage for d3mz6a_ (3mz6 A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (24 PDB entries)

8. Domain d3mz6a_: 3mz6 A: [181725]
   automated match to d1t64a_
   complexed with b3n, fe2, k

Details for d3mz6a_

PDB Entry: 3mz6, 2 Å

PDB Description: Crystal structure of D101L Fe2+ HDAC8 complexed with M344

PDB Compounds: (A:) Histone deacetylase 8

SCOPe Domain Sequences for d3mz6a_:

Sequence, based on SEQRES records:

>d3mz6a_ c.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgylcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvvi

Sequence, based on observed residues (ATOM records):

>d3mz6a_ c.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegeyglgylcpategifdyaaaiggatitaaqclidgmckvainwsggw
hhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslh
kfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavv
lqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgv
ilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvvi

Timeline for d3mz6a_:

• d3mz6a_ first appeared in SCOPe 2.01
  
• d3mz6a_ appears in SCOPe 2.04
  
• d3mz6a_ is called d3mz6a1 in SCOPe 2.06
  
• d3mz6a_ appears in the current release, SCOPe 2.08, called d3mz6a1