SCOPe 2.08: Domain d3mz6a1: 3mz6 A:14-377

Lineage for d3mz6a1 (3mz6 A:14-377)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

8. Domain d3mz6a1: 3mz6 A:14-377 [181725]
   Other proteins in same PDB: d3mz6a2
   automated match to d1t64a_
   complexed with b3n, fe2, k

Details for d3mz6a1

PDB Entry: 3mz6, 2 Å

PDB Description: Crystal structure of D101L Fe2+ HDAC8 complexed with M344

PDB Compounds: (A:) Histone deacetylase 8

SCOPe Domain Sequences for d3mz6a1:

Sequence, based on SEQRES records:

>d3mz6a1 c.42.1.2 (A:14-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgylcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvv

Sequence, based on observed residues (ATOM records):

>d3mz6a1 c.42.1.2 (A:14-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegeyglgylcpategifdyaaaiggatitaaqclidgmckvainwsggw
hhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslh
kfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavv
lqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgv
ilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv

Timeline for d3mz6a1:

• d3mz6a1 first appeared in SCOPe 2.01, called d3mz6a_
  
• d3mz6a1 appears in SCOPe 2.07