Lineage for d3mxfa_ (3mxf A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1992366Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 1992367Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 1992467Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 1992468Protein automated matches [190615] (7 species)
    not a true protein
  7. 1992472Species Human (Homo sapiens) [TaxId:9606] [187641] (355 PDB entries)
  8. 1992507Domain d3mxfa_: 3mxf A: [181665]
    automated match to d1jm4b_
    complexed with dms, edo, iod, jq1

Details for d3mxfa_

PDB Entry: 3mxf (more details), 1.6 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1
PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d3mxfa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3mxfa_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3mxfa_:

Click to download the PDB-style file with coordinates for d3mxfa_.
(The format of our PDB-style files is described here.)

Timeline for d3mxfa_: