SCOPe 2.03: Domain d3mvha_: 3mvh A:

Lineage for d3mvha_ (3mvh A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d3mvha_: 3mvh A: [181595]
   automated match to d1o6ka_
   complexed with mn, wfe

Details for d3mvha_

PDB Entry: 3mvh, 2.01 Å

PDB Description: crystal structure of akt-1-inhibitor complexes

PDB Compounds: (A:) v-akt murine thymoma viral oncogene homolog 1 (AKT1)

SCOPe Domain Sequences for d3mvha_:

Sequence, based on SEQRES records:

>d3mvha_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlqn
srhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldyl
hseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevledn
dygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgll
kkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeefta
qmititppdqddsmecvdserrphfpqfdysa

Sequence, based on observed residues (ATOM records):

>d3mvha_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vtmnefeylkllgkgtfgkvilvkekatgryyamkilkkevivakdevahtltenrvlqn
srhpfltalkysfqthdrlcfvmeyanggelffhlsrervfsedrarfygaeivsaldyl
hseknvvyrdlklenlmldkdghikitdfglckegikdgatmktfcgtpeylapevledn
dygravdwwglgvvmyemmcgrlpfynqdheklfelilmeeirfprtlgpeaksllsgll
kkdpkqrlgggsedakeimqhrffagivwqhvyekklsppfkpqvtsetdtryfdeefta
qrphfpqfdysa

Timeline for d3mvha_:

• d3mvha_ first appeared in SCOPe 2.01
  
• d3mvha_ appears in SCOPe 2.02
  
• d3mvha_ appears in SCOPe 2.04
  
• d3mvha_ appears in the current release, SCOPe 2.08