SCOPe 2.06: Domain d3msxa_: 3msx A:

Lineage for d3msxa_ (3msx A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein RhoA [52612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52613] (26 PDB entries)
   Uniprot P61586 2-181

8. Domain d3msxa_: 3msx A: [181539]
   Other proteins in same PDB: d3msxb_
   automated match to d1cxza_
   complexed with gdp, mg, mgf

Details for d3msxa_

PDB Entry: 3msx, 1.65 Å

PDB Description: crystal structure of rhoa.gdp.mgf3 in complex with gap domain of arhgap20

PDB Compounds: (A:) transforming protein rhoa

SCOPe Domain Sequences for d3msxa_:

Sequence; same for both SEQRES and ATOM records:

>d3msxa_ c.37.1.8 (A:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
irkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtagq
edydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrn
dehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

Timeline for d3msxa_:

• d3msxa_ first appeared in SCOPe 2.01
  
• d3msxa_ appears in SCOPe 2.05
  
• d3msxa_ appears in SCOPe 2.07
  
• d3msxa_ appears in the current release, SCOPe 2.08