SCOPe 2.08: Domain d3ms9a1: 3ms9 A:230-498

Lineage for d3ms9a1 (3ms9 A:230-498)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Abelsone tyrosine kinase (abl) [56166] (2 species)
   PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56167] (16 PDB entries)

8. Domain d3ms9a1: 3ms9 A:230-498 [181523]
   Other proteins in same PDB: d3ms9a2, d3ms9b2
   automated match to d1opjb_
   complexed with cl, ms9, sti

Details for d3ms9a1

PDB Entry: 3ms9, 1.8 Å

PDB Description: ABL kinase in complex with imatinib and a fragment (FRAG1) in the myristate pocket

PDB Compounds: (A:) Tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3ms9a1:

Sequence, based on SEQRES records:

>d3ms9a1 d.144.1.7 (A:230-498) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
pnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaav
mkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqiss
ameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtape
slaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvy
elmracwqwnpsdrpsfaeihqafetmfq

Sequence, based on observed residues (ATOM records):

>d3ms9a1 d.144.1.7 (A:230-498) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
pnydkwemertditmkhklgggqygevyegvwkkysltvavktlveeflkeaavmkeikh
pnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqissameyle
kknfihrdlaarnclvgenhlvkvadfglsrlgdtytahagakfpikwtapeslaynkfs
iksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwq
wnpsdrpsfaeihqafetmfq

Timeline for d3ms9a1:

• d3ms9a1 first appeared in SCOPe 2.01, called d3ms9a_
  
• d3ms9a1 appears in SCOPe 2.07