SCOPe 2.06: Domain d3mpqa_: 3mpq A:

Lineage for d3mpqa_ (3mpq A:)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein Na(+):neurotransmitter symporter homologue LeuT [161072] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [161073] (38 PDB entries)
   Uniprot O67854 5-513

8. Domain d3mpqa_: 3mpq A: [181489]
   automated match to d2a65a1
   complexed with bog, cl, leu, mtn, na; mutant

Details for d3mpqa_

PDB Entry: 3mpq, 2.25 Å

PDB Description: i204r1 mutant of leut

PDB Compounds: (A:) Transporter

SCOPe Domain Sequences for d3mpqa_:

Sequence, based on SEQRES records:

>d3mpqa_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsil
irgiskgierfakiamptlfclavflvirvflletpngtaadglnflwtpdfeklkdpgv
wiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaav
affgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpm
iafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliif
fwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtv
witrfyiiglflfltflvflaerrrnh

Sequence, based on observed residues (ATOM records):

>d3mpqa_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpepdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgis
kgierfakiamptlfclavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaav
gqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaffgv
anavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafle
delklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwifg
adkaweeinrggiikvpriyyyvmryitpaflavllvvthwtvwitrfyiiglflfltfl
vflaerrrnh

Timeline for d3mpqa_:

• d3mpqa_ first appeared in SCOPe 2.01
  
• d3mpqa_ appears in SCOPe 2.05
  
• d3mpqa_ appears in SCOPe 2.07
  
• d3mpqa_ appears in the current release, SCOPe 2.08