Lineage for d3mpea_ (3mpe A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154672Protein (Pro)cathepsin S [82566] (1 species)
  7. 2154673Species Human (Homo sapiens) [TaxId:9606] [82567] (23 PDB entries)
  8. 2154712Domain d3mpea_: 3mpe A: [181479]
    automated match to d1gloa_
    complexed with n2a; mutant

Details for d3mpea_

PDB Entry: 3mpe (more details), 2.25 Å

PDB Description: Crystal structure of human Cathepsin-S C25S mutant with bound drug
PDB Compounds: (A:) cathepsin S

SCOPe Domain Sequences for d3mpea_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3mpea_ d.3.1.1 (A:) (Pro)cathepsin S {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3mpea_:

Click to download the PDB-style file with coordinates for d3mpea_.
(The format of our PDB-style files is described here.)

Timeline for d3mpea_: