SCOPe 2.03: Domain d3mb7a_: 3mb7 A:

Lineage for d3mb7a_ (3mb7 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (34 PDB entries)

8. Domain d3mb7a_: 3mb7 A: [180993]
   automated match to d1jwha_
   complexed with 14i, so4

Details for d3mb7a_

PDB Entry: 3mb7, 1.65 Å

PDB Description: Human CK2 catalytic domain in complex with a difurane derivative inhibitor (AMR)

PDB Compounds: (A:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d3mb7a_:

Sequence; same for both SEQRES and ATOM records:

>d3mb7a_ d.144.1.7 (A:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdq

Timeline for d3mb7a_:

• d3mb7a_ first appeared in SCOPe 2.01
  
• d3mb7a_ appears in SCOPe 2.02
  
• d3mb7a_ appears in SCOPe 2.04
  
• d3mb7a_ appears in the current release, SCOPe 2.08