SCOPe 2.02: Domain d3m37a_: 3m37 A:

Lineage for d3m37a_ (3m37 A:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein automated matches [190044] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (122 PDB entries)

8. Domain d3m37a_: 3m37 A: [180780]
   Other proteins in same PDB: d3m37l_
   automated match to d1c5md_
   complexed with ca, m37

Details for d3m37a_

PDB Entry: 3m37, 1.9 Å

PDB Description: Factor XA in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC602)

PDB Compounds: (A:) coagulation factor x

SCOPe Domain Sequences for d3m37a_:

Sequence; same for both SEQRES and ATOM records:

>d3m37a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d3m37a_:

• d3m37a_ first appeared in SCOPe 2.01
  
• d3m37a_ appears in SCOPe 2.03
  
• d3m37a_ appears in the current release, SCOPe 2.08