Lineage for d3lz3a_ (3lz3 A:)

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 968086Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 969532Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 969533Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 969575Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 969576Species Human (Homo sapiens) [TaxId:9606] [51437] (82 PDB entries)
    Uniprot P15121
  8. 969588Domain d3lz3a_: 3lz3 A: [180651]
    automated match to d1el3a_
    complexed with 388, br, cit, nap; mutant

Details for d3lz3a_

PDB Entry: 3lz3 (more details), 1.03 Å

PDB Description: Human aldose reductase mutant T113S complexed with IDD388
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d3lz3a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3lz3a_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwpsgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfh

SCOPe Domain Coordinates for d3lz3a_:

Click to download the PDB-style file with coordinates for d3lz3a_.
(The format of our PDB-style files is described here.)

Timeline for d3lz3a_: