SCOPe 2.05: Domain d3lmpa_: 3lmp A:

Lineage for d3lmpa_ (3lmp A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (94 PDB entries)
   Uniprot P37231 232-505

8. Domain d3lmpa_: 3lmp A: [180397]
   automated match to d2p4ya1
   protein/DNA complex; complexed with cek

Details for d3lmpa_

PDB Entry: 3lmp, 1.9 Å

PDB Description: crystal structure of the ppargamma-lbd complexed with a cercosporamide derivative modulator

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3lmpa_:

Sequence, based on SEQRES records:

>d3lmpa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d3lmpa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfeq
skevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlasl
mnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviil
sgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqll
qvikktetdmslhpllqeiykdly

Timeline for d3lmpa_:

• d3lmpa_ first appeared in SCOPe 2.01
  
• d3lmpa_ appears in SCOPe 2.04
  
• d3lmpa_ appears in SCOPe 2.06
  
• d3lmpa_ appears in the current release, SCOPe 2.08