SCOPe 2.07: Domain d3le8b_: 3le8 B:

Lineage for d3le8b_ (3le8 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.4: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63976] (2 proteins)
   contains C-terminal subdomain similar to one structural repeat of the Creatinase/aminopeptidase family
   automatically mapped to Pfam PF02569

6. Protein Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63977] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [89615] (48 PDB entries)

8. Domain d3le8b_: 3le8 B: [180220]
   automated match to d1n2ga_
   complexed with 2b5, edo, eoh, gol

Details for d3le8b_

PDB Entry: 3le8, 1.7 Å

PDB Description: crystal structure of mycobacterium tuberculosis pantothenate synthetase at 1.70 angstrom resolution in complex with 2-(2- ((benzofuran-2-carboxamido)methyl)-5-methoxy-1h-indol-1-yl)acetic acid

PDB Compounds: (B:) Pantothenate synthetase

SCOPe Domain Sequences for d3le8b_:

Sequence, based on SEQRES records:

>d3le8b_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqp
gplaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldva
vvgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravld
aapgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieig

Sequence, based on observed residues (ATOM records):

>d3le8b_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
maipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgs
vvvvsifvnpmrtpdddlaqlraegveiaftpttaamypdglrttvqpgplaaeleggpr
pthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptvreadg
lamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvavdylel
rdiglgpmplngsgrllvaarlgttrlldniaieig

Timeline for d3le8b_:

• d3le8b_ first appeared in SCOPe 2.01
  
• d3le8b_ appears in SCOPe 2.06
  
• d3le8b_ appears in the current release, SCOPe 2.08