SCOPe 2.08: Domain d3kqda_: 3kqd A:

Lineage for d3kqda_ (3kqd A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (141 PDB entries)

8. Domain d3kqda_: 3kqd A: [179554]
   Other proteins in same PDB: d3kqdl_
   automated match to d1c5md_
   complexed with lgl, na

Details for d3kqda_

PDB Entry: 3kqd, 2.75 Å

PDB Description: factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1, 2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4- yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)- one

PDB Compounds: (A:) factor Xa heavy chain

SCOPe Domain Sequences for d3kqda_:

Sequence; same for both SEQRES and ATOM records:

>d3kqda_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d3kqda_:

• d3kqda_ first appeared in SCOPe 2.01
  
• d3kqda_ appears in SCOPe 2.07