SCOPe 2.08: Domain d3kmga_: 3kmg A:

Lineage for d3kmga_ (3kmg A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d3kmga_: 3kmg A: [179448]
   automated match to d3prga_
   protein/DNA complex; complexed with 538

Details for d3kmga_

PDB Entry: 3kmg, 2.1 Å

PDB Description: the x-ray crystal structure of ppar-gamma in complex with an indole derivative modulator, gsk538, and an src-1 peptide

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3kmga_:

Sequence, based on SEQRES records:

>d3kmga_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
adlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkhit
plqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiyt
mlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifi
aviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivte
hvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3kmga_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
adlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikeqske
vairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnk
dgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgd
rpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvi
kktetmslhpllqeiykdl

Timeline for d3kmga_:

• d3kmga_ first appeared in SCOPe 2.01
  
• d3kmga_ appears in SCOPe 2.07